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Learning objectives

Treatment of multidrug-resistant tuberculosis (MDR-TB) is now regarded as an essential component of international standards of TB care, with MDR-TB treatment currently being integrated into expanded Directly Observed Treatment, Short-course (DOTS) programmes for TB control. However, unlike DOTS, treatment of MDR-TB is complicated and expensive, requiring considerable expertise and resources. This Course is aimed at medical practitioners involved in the management of MDR-TB patients, under the guiding principles of the expanded DOTS framework.

The Course presupposes essential knowledge of TB transmission, pathogenesis, and the international DOTS strategy for TB control. The Course aims to facilitate self-study by medical practitioners of contemporary, evidence-based standards for diagnosis and clinical management of MDR-TB in a variety of geographical, economic and social settings.

Since MDR-TB treatment is a programmatic activity and treatment of patients should preferably be conducted under guidance of National TB Control Programmes, electronic links to relevant international policy guidelines have been provided.

Course fee

No course fee will be charged from those who want to complete the course.


The course is accredited by The Norwegian Medical Association and The Foundation for Professional Development in Pretoria, South Africa, with 22 hours/points in post-graduate and continuing education.

Course instruction

The course title (in red, at the top of the page) will always return you to this page, the start page of the course.

Below is an index which you may use to navigate between the different chapters of this course.

Each chapter has one or several lessons, and at least one test. All tests must be completed before you may request a diploma.


All reasonable precautions have been taken by the World Medical Association, the Foundation for Professional Development and the Norwegian Medical Association to verify the information contained in this publication. However this course is being distributed without warranty of any kind, either express or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Medical Association, the Foundation for Professional Development and the Norwegian Medical Association be liable for damages arising from its use.

As research and experience with MDR-TB progress we do expect that WHO will update it’s guidelines. We do our best to incorporate changes into the course, however please visit the WHO web page to check for the latest versions of the guidelines.

The World Medical Association gratefully acknowledges

The partnership of Eli Lilly by a generous unrestricted educational grant and a tireless coordination of the humanitarian efforts in the NGO community to fight TB.

The support by its constituent members
  • Foundation for Professional Development (FPD) the educational division of the South African Medical Association (SAMA)
  • The Norwegian Medical Association and its learning platform for transforming the course into the online format and making the course online available
  • The German Medical Association for coordinating this WMA project

The volunteer support by our advisory committee

  • Dr Oumou Bah-Sow, Tuberculosis Area of Work Division for AIDS, TB and Malaria (ATM) World Health Organization/Regional Office for Africa (WHO/AFRO), Zimbabwe
  • Dr. Liu Jianjun, National Center for Tuberculosis Control and Prevention, China
  • Dr. Yao Hongyan, National Center for Tuberculosis Control and Prevention, China
  • Dr. John Sbarbaro, University of Colorado, USA
  • Prof. Mohammad Reza Masjedi, National Research Institute of Tuberculosis and Lung Disease, Iran
  • Mr. Bjorn Hoftvedt, Norwegian Medical Association, Norway
  • Dr. Vaira Leimane, MDR Training Centre of Excellence, Latvia
  • Dr. Jose Caminero Luna, Consultant – IUATLD, Spain
  • Dr. Thelma Tupasi, Tropical Disease Foundation, Inc, Philippines

The work of some persons, who dedicated work to this program

  • Dr. Karin Weyer, Medical Research Council, South Africa, for her excellent authorship
  • Dr. Hernan Reyes, Switzerland, for contributing the chapter on TB and prisons
  • Dr. Patrizia Carlevaro, Switzerland, coordinating, inspiring and moving the MDR-TB work of the international NGO-community
  • Foundation for Professional Development, South Africa:
  • Dr. Elmie Castleman
  • Mrs. Ronel Chickory
  • Ms. Helga Swart
  • Prof. Pierre JT de Villiers from Stellenbosch University on behalf of Foundation for Professional Development.
  • Ms. Karoline Borgen, for making this work visible on the Internet
  • Mr. Bjorn Hoftvedt, for editing the manuscripts
  • Dr. Terje Vigen, Norway, for allocating resources from the Norwegian Medical Association
  • Dr. Ramin Pasa Parsi, Germany, for coordinating the WMA – project
  • Dr. Delon Human, Switzerland, for starting the project
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最后修改: 2013年01月11日 星期五 12:27